3. Compare characteristics of atypical antipsychotic drugs with those of typical phenothiazines and related antipsychotic drugs. 4. Describe the main elements of acute and longterm treatment of psychotic disorders. 5. State interventions to decrease adverse effects of antipsychotic drugs.
6. Eventually it was discovered that these medication had antipsychotic properties and they began developing the first generation antipsychotics (FGAs).
First Atypical antipsychotics are also known as second generation antipsychotics. Experts arent exactly sure how atypical antipsychotics work but they appear block certain chemical receptors in the brain, affecting levels of various neurotransmitters such as dopamine, acetylcholine, noradrenaline, or serotonin.
8. Classification of antipsychotics. Antipsychotic drugs were discovered in the 1950s and currently over 20 compounds are licensed. They vary in clinical effects and especially in unwanted effects. Antipsychotics are classified in a number of ways and this brief guide touches on selected aspects of classification. Atypical antipsychotics are also more likely to improve cognitive function.
Clozapine (classed as an atypical antipsychotic even though it is quite an old drug) also improves delusions and hallucinations and reduces the risk of suicide. Classification of typical and atypical antipsychotic drugs on the basis of dopamine D1, D2 and serotonin2 pKi values.
H Y Meltzer, S Matsubara and J C Lee Journal of Pharmacology and Experimental Therapeutics October 1989, 251 (1); Nov 13, 2011 The term atypical antipsychotics is the most commonly used for second generation antipsychotics. Based on their shared pharmacological properties, these drugs are also called dopamineserotonin antagonists. Nov 24, 2015 This health topic webpage is intended to provide basic information about mental health medications.
It is not a complete source for all medications available and should not be used as a guide for making medical decisions. Several atypical antipsychotics have a broader spectrum of action than the older medications, and C. Classification of Antipsychotics D. Pharmacological Profile of Each Category E. Clinical Usage. PSYCHOSIS A symptom of mental illnesses B. AtypicalSecond Generation Antipsychotics e.
g. clozapine, risperidone, olanzapine quetiapine, aripiprazole. FIRST GENERATION ANTIPSYCHOTICS